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Technology

Molecular Biologist / Research Scientist

Proto-Town

Ashby
Location
Lockhart, United States
Type
FullTime
Salary
Salary not specified
Posted
26 Jul 2026
THE ROLE We are building an automated biology platform and, and we are looking for a molecular biologist / research scientist to handle the core wet lab work: selection design, library construction, and readouts. RESPONSIBILITIES - Run end to end workflows, library through selection to characterized hits - Design selection strategy: stringency schedules, bottlenecks, counter-selections - Design FACS sorting and screening strategies, and interpret population trajectories across rounds MUST-HAVES 1. Cell culture: hands-on experience, ideally with yeast. 2. Molecular cloning: fundamentals (PCR amplification, Gibson assembly, Golden Gate assembly, transformations); experience with sequencing services. 3. Flow cytometry/FACS: gating strategies, staining, sample loading. NICE-TO-HAVES Yeast genetics and surface display · OrthoRep or other continuous hypermutation systems · phage display or PACE · SPR/BLI · NGS library prep and analysis · protein expression and purification · Opentrons, Hamilton, Tecan, or eVOLVER-class hardware. If you have never worked in yeast, apply anyway. We would rather hire for selection judgment and long-run discipline, and teach the organism.
THE ROLE We are building an automated biology platform and, and we are looking for a molecular biologist / research scientist to handle the core wet lab work: selection design, library construction, and readouts. RESPONSIBILITIES - Run end to end workflows, library through selection to characterized hits - Design selection strategy: stringency schedules, bottlenecks, counter-selections - Design FACS sorting and screening strategies, and interpret population trajectories across rounds MUST-HAVES 1. Cell culture: hands-on experience, ideally with yeast. 2. Molecular cloning: fundamentals (PCR amplification, Gibson assembly, Golden Gate assembly, transformations); experience with sequencing services. 3. Flow cytometry/FACS: gating strategies, staining, sample loading. NICE-TO-HAVES Yeast genetics and surface display · OrthoRep or other continuous hypermutation systems · phage display or PACE · SPR/BLI · NGS library prep and analysis · protein expression and purification · Opentrons, Hamilton, Tecan, or eVOLVER-class hardware. If you have never worked in yeast, apply anyway. We would rather hire for selection judgment and long-run discipline, and teach the organism.